Exemestane (Aromasin) Anti-estrogen Powder

Exemestane (Aromasin)

Brief info:

Product Category: Pharmaceutical raw materials and intermediates 

Product content: ≥ 99% 

CAS:107868-30-4

Molecular formula: C20H24O2

Molecular Weight:296.40

Packing specifications: 25kg / barrel 

Appearance: White or Almost White Crystalline Powder

Description:

Exemestane is also called Aromasin. It is only suitable for women who have had their menopause.

Many breast cancers are stimulated to grow by the female sex hormones estrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.

In women who have had their menopause, estrogen is mainly produced by changing androgens into estrogens. This process is called aromatization and happens mainly in the fatty tissues, muscle, and the skin. It needs a particular enzyme called aromatase.

It lowers the amount of estrogen in the body. In early breast cancer, taking Aromasin can help to stop breast cancer coming back. In advanced breast cancer, the cancer cells may grow more slowly or stop growing completely.

Dosage:

Exemestane reaches peak plasma concentrations within 2 hours following the oral administration of a 25 mg dose. The active life of the drug is between 24 and 30 hours. This is significant since it is quite shorter than for the non-steroidal inhibitors. A single oral dose of 25 milligrams of exemestane causes a relatively long-lasting reduction in plasma and urinary estrogen levels, with maximal suppression occurring approximately 2 to 3 days after dosing and persists for about 4 to 5 days.

It has been shown that 25 milligrams of exemestane are basically just as effective as 50 milligrams at suppressing estrogen, raising testosterone levels, and levels of IGF. It is, therefore, unnecessary to go higher in doses than 25 milligrams per day. Due to the active life of the compound exemestane should be administered roughly once every twenty-four hours.

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